27 Little Known Things About House M.D.

This article is based on "25 Fun Facts About House M.D.", "House M.D. IMDB Trivia", and "The Most (And Least) Medically Accurate Episodes Of House, M.D." If you're interested in reading more, check out the links at the bottom of the article.

2/27 A running joke on the series was that Cameron would suggest that the patient was suffering from lupus and House would reply, "It's never lupus." Except for the one time it was. In the season four episode "You Don't Want To Know" a patient was finally correctly diagnosed with the autoimmune disease.

3/27 During Hugh Laurie's audition process executive producer Bryan Singer said, "See, this is what I want, an American guy." Laurie is British.

4/27 The character Gregory House is based on Arthur Conan Doyle's protagonist Sherlock Holmes. Holmes is in turn based on Dr. Joseph Bell, a colleague of Doyle's who specialized in diagnostics. On the show House lives in apartment 221B, a nod to Sherlock Holmes living at 221B Baker Street.

5/27 The name House is also a nod to the medical acronym HOUSE (History Of USE) used to denote when a patient has a history of drug use or addiction.

6/27 The show's production company, Bad Hat Harry Productions, is a reference to the Jaws quote: "That's some bad hat, Harry."

7/27 The tagline "Humanity Is Overrated" was used when the show aired in Finland. However in 2007 when a gunman shot eight people to death in a Finnish school and used the same phrase the tagline was removed from the show's website.

8/27 Kal Penn was killed off the show because he asked to be allowed to leave the show to go work for the Obama Administration in the White House Office of Public Engagement.

9/27 Hugh Laurie's salary grew over the course of the show's eight seasons from $50,000 per episode in the first season to over $700,000 by the series finale.

10/27 Hugh Laurie's father is a doctor and Laurie has felt guilty over the idea of being paid more than his father to simply play a fake version of him.

11/27 Executive producer Bryan Singer appears in the first season episode "Sports Medicine" as the director of an anti-drug commercial.

12/27 Jennifer Morrison and Jesse Spencer dated for the first few seasons and became engaged in December 2006, around the same time that their character became a couple on the show. However they called off their engagement five months later and eventually their fictional relationship dissolved as well.

13/27 The show was nominated for 9 Golden Globes (winning 2), 25 Primetime Emmy Awards (winning 5), 16 Teen Choice Awards (winning 1) and 1 Peabody (which it won).

14/27 Lisa Edelstein left the show after shooting the season 7 finale. Creator David Shore said that if she had told them she wasn't coming back for the last season he would have ended the finale differently and written her character out in a more monumental way.

15/27 Hugh Laurie said that when he read the unnamed pilot he thought that James Wilson was the lead, not House. He couldn't imagine someone like House being the star of a show.

16/27 House is a polyglot. Throughout the series he is heard speaking English, Spanish, Portuguese, Russian, Hindi, and Mandarin.

17/27 Diagnostics and the Department of Diagnostic Medicine are fictional speciality/department created for the purpose of the show. Each character does have an actual speciality though: neurology (Foreman), immunology (Cameron), intensive care (Chase), plastic surgery (Taub), sports medicine (Taub), internal medicine (Hadley), and infectious disease and nephrology (House).

18/27 Hugh Laurie auditioned for the role of Gregory House via a self tape shot in a hotel bathroom in Namibia. He was shooting Flight of the Phoenix and says that the bathroom was "the only place with enough light".

19/27 Hugh Laurie is the only cast member to appear in every episode of the series.

20/27 Executive producer Paul Attanasio came up with the idea for the show after reading the New York Times Magazine column Diagnosis Club which features unusual medical cases. He pitched it as a medical procedural but creator David Shore revised the idea to be more of a character drama that used medicine as a vehicle for character development.

21/27 Patrick Dempsey was considered for the role of House before being cast as another doctor, Derek "McDreamy" Shepherd, on Grey's Anatomy.

22/27 Michael Weston portrayed the character Lucas Douglas with the intention of having a spin-off series about the character but producers eventually decided against it.

23/27 In the season 2 episode "Informed Consent" House says to a patient, "Pay no attention to the man behind the curtain." That patient was played by Joel Grey who played the Wizard of Oz in Wicked on Broadway.

24/27 Allison Cameron was written off the show because creator David Shore wanted to show that not every character around House would end up corrupted by him. He says it was very hard to let her go but ultimately it was the right decision for the show.

25/27 It was Hugh Laurie's idea for House to wear sneakers. The costume department had 37 pairs of Nike running shoes for him to choose from.

26/27 Mid-series Hugh Laurie confessed that he was starting to physically suffer from constantly limping. He didn't know if he could last the rest of the series because his knees were starting to chronically hurt from all the hip work. It caused a problem with his other auditions and roles as well, as every time he heard "rolling" he would automatically limp, regardless of the role.

27/27 Like most other medical shows on television the series employed doctors as consults to make sure the content was medically accurate. According to doctors who watch the show the most medically accurate episode was the season two episode "Clueless" wherein a man nearly suffocates when his tongue swells during sex. It ends up that his wife was poisoning him with gold sodium thiomalate, an old arthritis treatment.

Sources: 1, 2, 3

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